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Extending the Spectrum of Precompetitive Collaboration in Oncology Research El amor. Esa gran encrucijada specialty mental health and substance-useExtending the Spectrum of Precompetitive Collaboration in Oncology Research Despite spending more time and money in developing novel therapeutics, the success rate for new pharmacologic treatments has been poor. Although the research and development expenditures have grown 13 percent each year since 1970 (a 50 fold increase), the number of new drugs approved annually is no greater now than it was 50 years ago. Over the past decade, skyrocketing costs